Sunday, September 2, 2012

New U.N. Syria envoy tells regime change is needed

BEIRUT (AP) ? The U.N.'s new envoy to Syria told President Bashar Assad's regime on Saturday that change is both "urgent" and "necessary" and that it must meet the "legitimate" demands of the Syrian people, words that will not win the seasoned Algerian diplomat and international trouble shooter any friends in Damascus.

On his first day on the job, Lakhdar Brahimi also called on both sides to end violence in Syria, but said Assad's government bears more responsibility than anyone else to halt the bloodshed. These remarks were seemingly intended to push the Damascus government to ease off on military operations to create a better atmosphere for his peace mission.

His comments, made in New York, came as activists said rebels captured an air defense facility in the east of the country near the border with Iraq. The battle for control of Syria's largest city Aleppo meanwhile intensified, with government warplanes and ground forces pounding it with bombs and mortar rounds as rebel fighters fought off troops in the narrow alleys of the city's old quarter.

"I call on parties inside Syria to halt the fighting. Undoubtedly, this call is primarily directed to the government. More than others, it is the duty of governments, under any circumstances and anywhere, not just in Syria, to ensure security and stability for their people," Brahimi told al-Arabiya television in an interview.

"The need for change is urgent and necessary. The Syrian people must be satisfied and their legitimate demands are met," he said.

The latest violence in Aleppo shows that government forces are still struggling to regain full control of the city from the lightly-armed rebels nearly five weeks after they stormed their way into the city in a surprise offensive.

The Syrian Observatory for Human Right activist group said Saturday's clashes in Aleppo were concentrated in several tense neighborhoods ? Masaken Hanano, Bustan al-Qasr, Sukkari and Maysar. It reported injuries and damage to buildings, but gave no specific figures. Another activist group, the Local Coordination Committees, said the government was making heavy use of warplanes in attacking rebel areas.

For over a year after the uprising against Assad's rule began nearly 18 months ago, Aleppo and Damascus stayed relatively quiet. But in July, rebels launched a brazen attack on the two cities, capturing several neighborhoods. Government forces have regained most of the Damascus area but are being held to a stalemate in Aleppo, the nation's commercial capital and home to 3 million people.

In the east, the Observatory reported that rebels captured an air defense post in the town of al-Boukamal in the oil-rich province of Deir el-Zour that borders Iraq. The opposition has claimed advances in the area in recent days. A video released by activists showed soldiers purportedly captured by rebels at the post.

The authenticity of the video could not be independently confirmed.

There was no immediate response from the Syrian government to the comments made by Brahimi, who replaced Kofi Annan who quit after his six-point plan including an April 12 cease-fire failed to stop the Syrian civil war.

Brahimi said he had no new ideas to end the conflict and has yet to decide when to make his first visit Damascus in his new capacity.

"I don't have anything new except insisting on the necessity of ending the violence and starting a political process that has credibility and able to bring about peace and stability for the Syrian people," he said.

"A transitional political process is what is needed. There is no disagreement inside or outside Syria that a new situation or a new political framework is needed," he said, adding that since the government and the opposition are not talking to each other, they could use him as the go-between.

Addressing himself to the opposition, he said: "Realize that the situation is both difficult and dangerous and what is important is the interest of the entire people of Syria, not individuals or groups." He was apparently alluding to the fact that most rebels fighting the government are drawn from Syria's Sunni Muslim majority. Assad and many in the nation's ruling elite are members of the Alawite sect, an offshoot of Shiite Islam. Syria's 23 million people also include a sizable Christian minority.

Brahimi refused to directly comment on statements made in Moscow Saturday by Foreign Minister Sergey Lavrov that the international community should try to persuade all sides in the Syrian conflict to stop the violence and that it would be naive or provocative to ask the Syrian government to stop the violence first.

Asked about the Russian's comments, he said: "He is responsible for his words and has the right to say that all parties must stop the violence. But, undoubtedly, I don't believe that Lavrov differs with my view that the responsibility of the government is greater than that of that the others."

The Syrian conflict has its roots in mostly peaceful street protests that started in March last year. It has since morphed into a civil war, with at least 20,000 people killed so far, according to rights activists.

In addition to Aleppo and the east, fighting continued in Damascus, where, despite the government's offensive, opposition fighters continue to stage attacks using hit-and-run tactics in neighborhoods where they enjoy popular support, activists say.

Early Saturday, government forces bombarded the capital's southern neighborhood of Tadamon following street fighting with rebels there, the Observatory said. The LCC said troops also shelled the nearby neighborhood of Hajar Aswad.

Activists also reported the discovery of dead bodies shot execution style in a Damascus suburb where fighting and shelling have been intense over the past week. They said a total of 17 bodies were found on Saturday in Kfar Batna east of the capital, a day after government forces stormed the town of some 45,000 people.

Activist Mohammed Saeed, speaking via Skype from the Damascus area, said the dead included three nurses from a local clinic that treated civilians wounded by regime shelling.

Last week, activist reports spoke of anywhere between 300 and 600 people killed in the Damascus suburb of Daraya during days of shelling and a killing spree by troops who stormed the town after heavy fighting. Saeed said another seven bodies were found in Daraya on Saturday.

In the Damascus neighborhood of Qadam, the bodies of five unidentified people were found on Saturday, all shot execution style, according to the Observatory, an activist group.

None of these reports could be independently verified.

By late Saturday, the LCC said 156 people were killed across Syria.

____

Associated Press correspondent Bassem Mroue contributed to this report.

Source: http://news.yahoo.com/un-syria-envoy-tells-regime-change-needed-205717891.html

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Eastwood shows how clever those GOP spin doctors are (Americablog)

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Lucky: Stanford sloppy in win over San Jose State

STANFORD, Calif. (AP) ? David Shaw has never been one to show too much emotion, keeping his cool no matter the circumstances. He heaps praise on players but isn't afraid to call out poor performances, either.

Late Friday night was different.

Following No. 21 Stanford's season-opening 20-17 victory over San Jose State, the second-year coach had little patience trying to explain one of the most frustrating games of his tenure. At one point, a reporter asked him if this season might be more fun without No. 1 overall pick Andrew Luck, considering the room for growth his young team could make.

"Fun?" Shaw asked. "For whom?"

Certainly not for the coach.

The post-Luck era got off to a disappointing debut, with former backup Josh Nunes throwing for 125 yards and a touchdown, and struggling to move the offense in the running game before getting bailed out by Jordan Williamson's rejuvenated right foot.

Williamson kicked a career-long 46-yard field goal and the go-ahead score from 20 yards to save Stanford from what would've been a stunning start to this season.

"It was real close," senior running back Stepfan Taylor said. "But close will get you beat in a heartbeat."

Almost did.

Williamson, who missed three field goals ? including a potential game-winner in regulation ? in a 41-38 overtime loss to Oklahoma State in the Fiesta Bowl on Jan. 2, might have been the only one with a reason to hold his head down following that fantastic effort from both sides.

Now he might be the only Stanford player who should hold his head high after a shaky start this season.

Nunes finished 16 for 26 with no interceptions in place of Luck, but the offense stalled when it counted most ? and it almost cost the Cardinal (1-0) dearly against the Spartans (0-1).

"We were close to doing a lot of really good things tonight," Nunes said. "But close doesn't always win football games."

It usually loses them.

The David Fales-Blake Jurich quarterback combo gave Stanford fits until De'Leon Eskridge fumbled in Spartans territory late in the third quarter. That set up Williamson's tiebreaking kick, giving the redshirt sophomore a small stroke of redemption after months of public silence and tissues and tears back home.

"That shows the kind of person he is," said Taylor, who ran for 116 yards and a touchdown. "That's a lot of pressure, and missing them in the Fiesta Bowl you know all the pressure is going to be on him. He's cold blooded."

So was San Jose State's passing game.

Fales threw for 216 yards with one touchdown and an interception that landed in the hands of Ed Reynolds with 71 seconds remaining to seal Stanford's victory. Jurich ran for 32 yards and a score.

The fight Stanford showed so many times behind Luck dissolved.

With the two-time Heisman Trophy finalist now with the Indianapolis Colts, the Cardinal converted only 2 of 13 third downs (although it was 2 for 3 on fourth downs) and allowed the Spartans to move methodically at times down field. San Jose State outgained Stanford 288 to 280 in total yards.

Stanford beat San Jose State 57-3 last year and has won five straight meetings.

"Since we got our butts kicked here last year, we could have won every game since," third-year San Jose State coach Mike MacIntyre said. "So we're making progress. We're getting bigger, stronger and faster. We're making strides. But in no way, shape or form is this a moral victory. We're a better football team, but we have to finish it off."

Taylor ran for 38 yards almost untouched until a defender tackled him on the game's first drive. Remound Wright converted a fourth-and-1 from the 10-yard line, and Taylor dived over the pile for a 1-yard TD on fourth down to give Stanford a 7-0 lead.

Nunes quickly led Stanford down field again and tossed a perfect ball in the corner on a stop-and-go route by Drew Terrell for an 11-yard score and his first career touchdown pass.

The first-game hiccups eventually surfaced, though, and bubbling later than expected until they almost completely popped Stanford's season.

Game-clock management became an issue on Stanford's final drive of the first half, tossing a short pass over the middle to tight end Zach Ertz, then throwing incomplete and running on third down to settle for a field goal. Williamson, who tore a groin muscle last October and was never the same when he returned, made his career-high 46-yarder as time expired to extend Stanford's lead to 17-3.

"I feel like I finally put everything from the past in the past and now I can focus on the future," a smiling Williamson said. "It was a tremendous feeling."

All the same problems that plagued the Cardinal defense in losses last year to Oregon and Oklahoma State ? no cornerback coverage, poor open-field tackling and quarterback pressure when it counts ? looked even worse with two new starting safeties.

Jurich ran for a short touchdown on San Jose State's first possession of the third quarter and Fales floated a 21-yard touchdown pass to Noel Grigsby to tie the score at 17-all late in the third quarter.

Fales, who transferred from Monterey Peninsula Community College in the spring, redshirted at Nevada in 2009 but quickly had San Jose State in position for the season's first shocking upset.

One mistake ended all that.

Reynolds stripped Eskridge on a pitch play, and Usua Amanam recovered the fumble at San Jose State's 38-yard line. Stanford's offense stalled again, and Williamson made his second field goal.

San Jose State stuffed Taylor on fourth-and-1 with fewer than 7 minutes to play, sending MacIntyre jumping and high-fiving all over the sideline and on the field. Fales and the offense failed to even get a first down on the next two possessions and Reynolds stepped in front of his final pass to close out San Jose State's rally.

___

Follow Antonio Gonzalez at: www.twitter.com/agonzalezAP

Source: http://news.yahoo.com/lucky-stanford-sloppy-win-over-san-jose-state-082149228.html

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CarloAtYourServ: Top 5: Central Florida's largest catering companies http://t.co/KtKT0AMn

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Saturday, September 1, 2012

The beat goes on: Research yields two 'firsts' regarding protein crucial to human cardiac function

ScienceDaily (Aug. 31, 2012) ? Florida State University researchers led by physics doctoral student Campion Loong have achieved significant benchmarks in a study of the human cardiac protein alpha-tropomyosin, which is an essential, molecular-level component that controls the heart's contraction on every beat.

Using an imaging method called atomic force microscopy, Loong achieved two "firsts": the first direct imaging of individual alpha-tropomyosin molecules, which are very small -- roughly 40 nanometers long -- and the first demonstrated examples of a measure of the human cardiac protein's flexibility. From there, he established a baseline of how flexible a normal version of the protein is supposed to be in a healthy human heart.

"This basic research is important to broadening our understanding of how the human heart functions normally at the molecular level," Loong said. "The flexibility of alpha-tropomyosin dictates how effectively or properly the heart muscle will contract on each beat and has implications for keeping the heart free of cardiovascular disease.

"Before this study, we did not know how flexible this protein was," Loong said. "Using these results, now we can conduct subsequent studies to compare disease-related mutants of this protein to see how much they deviate from normal versions."

Loong served as the lead author of the paper "Persistence Length of Human Cardiac a-Tropomyosin Measured by Single Molecule Direct Probe Microscopy," which was published in the journal PLoS ONE. He conducted the research with physics Professor Huan-Xiang Zhou and biological science Professor P. Bryant Chase, both of Florida State.

When an electrical signal is generated in the heart to make it contract, calcium is released inside each heart muscle cell. The calcium then binds to a protein called troponin, and that triggers the "flexing movement" of alpha-tropomyosin, which allows another protein called myosin -- the motor protein -- to interact with the troponin/tropomyosin actin filaments. This series of events is what generates the heart's contraction that pumps blood. A subsequent removal of calcium inside each heart cell is what relaxes the heart, which allows the heart to fill with blood to be pumped on the next beat.

"Alpha-tropomyosin is a key element that makes the calcium signal either turn the heart on, making it contract, or turn it off, making it relax," Chase said. "There is an optimal range of flexibility of alpha-tropomyosin for the normal heart to function properly. The molecule can be too stiff or it can be too flexible, either of which could lead to cardiovascular disease. What we ultimately think is that evolution has tuned the mechanical properties of these proteins for optimal function in the heart."

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The above story is reprinted from materials provided by Florida State University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Campion K. P. Loong, Huan-Xiang Zhou, P. Bryant Chase. Persistence Length of Human Cardiac ?-Tropomyosin Measured by Single Molecule Direct Probe Microscopy. PLoS ONE, 2012; 7 (6): e39676 DOI: 10.1371/journal.pone.0039676

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/UK6yNC4vlgE/120831103830.htm

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New Jersey shopping plaza shootout leaves 3 dead

Three people died early this morning, including an alleged gunman who apparently killed himself, after a shooting inside a New Jersey shopping plaza.

Police in New Jersey responded to shots inside a Pathmark supermarket on Route 9 in Old Bridge, N.J., at 4 a.m.

"This is the worst phone call a mayor can receive," Mayor Owen Henry told NewJersey.com of the information he obtained about 6:30 a.m. "You can prepare for these things but you can't prevent them."

The suspect has been identified as a man in his 20s who was a current or former employee, WABC-TV reported. There's no word on his motive.

Authorities believe the man killed two before turning the gun on himself, according to WABC.

Several employees were inside the store, which was preparing to open at 6 a.m. Two windows near the entrance to the Pathmark were shot out.

Numerous employees were taken across the street to a T.G.I. Friday's and many are being treated for trauma at waiting ambulances.

The scene is now under control, according to WABC, and there are emergency responders in the plaza parking lot who have been standing in front of the store for the past hour.

Also Read

Source: http://gma.yahoo.com/jersey-shopping-plaza-shooting-leaves-three-dead-110051012--abc-news-topstories.html

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Travel Insurance May Require Your Medical History: Tell Your ...

All too often, when travel insurance claims are denied (which is rare), clients complain that their doctor didn?t tell them everything that was in their record and they, therefore, couldn?t complete their medical applications accurately. It?s up to you to put your doctor on notice.

Doctors have an ethical obligation to their licensing and/or accreditation authorities to reveal the results of all tests, investigations, consultation reports to their patients?whether they think them important or not.? But how often do I here travellers complain that because their doctor didn?t tell them about a first or second degree heart block, or a minor atrial fibrillation, or an unexplained finding on a CT scan of the liver or biliary tract, their insurer denied their claim for a hospitalization in the U.S. or some other foreign country because they didn?t disclose their health status accurately or completely?

Too often, doctors do this because the condition? in question may not be life-threatening, or they don?t want to worry an elderly patient about something they can?t do anything about anyway, or they don?t want to interrupt a patient?s five-month vacation in Florida.? They do this because they assume that since their patient has private travel insurance they will be covered the way they are at home, and so they don?t need to take the time to discuss the actual insurance policy with their patient.

Yet this kind of thinking can have a disastrous effect on the patient, who because of lack of knowledge of a pre-existing condition, or failure to inform the insurer of a positive test result, can have their emergency medical expense claim denied.

Canadian family doctors, many of who have plenty of snowbirds and boomers on their patient roles, should make the effort to learn at least the basics of travel insurance.? But they don?t teach travel insurance in medical school and there are no continuing medical education credits for learning about it. So it?s up to you to tell them you must know want is in your medical record: it?s your record, and it?s not the doctor who will have to pay the foreign hospital bill if your claim is denied.

It?s too easy to blame the insurer when that happens.

Without private travel insurance, many of the millions of Canadians who travel out of the country regularly could not afford to travel were it not for travel insurance.? They couldn?t take the risk, because their government health insurance abandons them as soon as they leave the country: they pay only a pittance of out of country medical emergency costs.? Private travel insurers must pay all that the provincial plans do not pay?and that is a lot.

Consequently, private travel insurers need to place limits on what they will cover and who they will cover. They can?t, for the prices they charge, cover you as medicare does at home. That?s why all insurance plans have eligibility limits and exclusions. The benefits they offer are generous, although its true enough that travel insurers and the agents who sell their plans, as a whole, have not done a good enough job explaining what they don?t cover.? They?re much better at telling you what they do cover.

But that should not leave doctors off the hook. And the only realistic way for doctors to become responsive to your needs as an insured patient heading out of the country is for you to make them understand that you require full disclosure.? If you need extra time to complete a medical application, go to your doctor and pay him or her to help you. If you don?t quite understand why you?re taking a certain medication or why you have been referred for tests, demand answers.

Source: http://travelinsurancefile.com/headlines/travel-insurance-may-require-your-medical-history-tell-your-doctor/

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